Border Image

Scientific Evidence

The incredible advantage of Cardisiography lies in the early detection of heart disease in people who are still completely asymptomatic.

Studies show results that demonstrate the clear benefits of the method for early detection of reduced blood flow to the heart muscle.

Cardisio Peer Reviewed Study

Frankfurt, January 16, 2020: In the current issue, the renowned journal “Journal of Electrocardiology” publishes a peer-reviewed study demonstrating the impressive precision of Cardisiography in screening coronary heart disease. The article provides results on the sensitivity and specificity of Cardisiography: The sensitivity is 97% for male subjects, 90% for females, i.e. 97% of sick men are recognized as diseased and 90% of women. In terms of specificity, the women who participated in the study are ahead of the men with 74% with 76%, i.e. 76% of healthy women are recognized as healthy and 74% of men. Cardisiography is the first procedure that can be used to determine the risk of coronary heart disease (CHD) in asymptomatic people non-invasively, quickly and cheaply.

Download Journal

Cardisio Validation Study Sana Heart Center Cottbus

Frankfurt, March 10, 2020: For the second time within a short period of time, a clinical study has come to the conclusion that Cardisiography achieves comparable results in the detection of coronary heart disease (CHD) as the current gold standard, coronary angiography.

The team led by Dr. Temirlan Erkenov from the Department of Cardiac Surgery at SANA Heart Center in Cottbus, Germany, concluded that: “… Cardisiography is a simple, precise and highly valid method that is suitable as a non-invasive diagnostic modality for the initial assessment of stable CHD in a clinical setting…” (Cardisiography as a novel non-invasive diagnostic tool for the detection of coronary artery disease at rest – a first prospective study of diagnostic accuracy; Temirlan Erkenov, Tomasz Stankowski, Oliver Grimmig, Sören Just, Prof. Oleg Remizov, Prof. Dirk Fritsche)

The study included data from 106 patients in whom coronary angiography was indicated and performed. Subsequently, Cardisiography was performed, the result of which was blindly correlated with that of coronary angiography. The result: In a total of 86 of the 106 patients, vascular disease was confirmed by coronary angiography. Cardisiography identified 82 of the 86 cases (95.4 percent), while conventional echocardiography detected only 12 cases. This results in a sensitivity of 95.4 percent for Cardisiography, a specificity of 90 percent and a positive predictive value of 97.6 percent for CHD.

“In Western countries, coronary heart disease is one of the leading causes of death and a common cause of physical disability. The reason for the severe course is the fact that the initial manifestation of the disease can be a heart attack or sudden cardiac death. Cardisiography is a new, easy-to-use and examiner-independent technology that uses vector cardiography with the modern analysis possibilities of artificial intelligence,” the authors explain the reason for conducting the study – and for its convincing course.

Download abstract

Study Heart Center Bad Oeynhausen:, Germany Comparison of Cardisiography (CSG) with myocardial SPECT in suspected CHD and known CHD

Study at the Heart and Diabetes Center North Rhine-Westphalia in Bad Oeynhausen confirms the diagnostic relevance of Cardisiography.

Comparison of Cardisiography (CSG) with myocardial SPECT in suspected and known CHD:

  • Cardisiography (CSG) shows a significant correlation with MPS in pre-diagnostic testing for CHD
  • A normal CSG correlates with a normal to low pathologic MPS, corresponding to a high negative predictive value of 98%
  • CSG is suitable as a pre-selection tool for GP or cardiology practices to decide on non-invasive imaging in patients with suspected CHD

Download Overview

Complementary Studies And Literature On Our Technology

The Poynting Vector: Power and Energy in Electromagnetic Fields

Carpenter KH. The Poynting vector: power and energy in electromagnetic fields. Department of Electrical and Computer Engineering. Kansas State University (2004)


Spatial Vector Electrocardiography; The Clinical Characteristics of S-T and T Vectors

Grant RP, Estes EH Jr, Doyle JT. Spatial vector electrocardiography; the clinical characteristics of S-T and T vectors. Circulation. 1951 Feb;3(2):182-97.


Cardiogoniometry: A New Noninvasive Method for Detection of Ischemic Heart Disease

Saner H, Baur HR, Sanz E, Gurtner HP. Cardiogoniometry: a new noninvasive method for detection of ischemic heart disease. Clin Cardiol. 1983 May;6(5):207-10.


Cardiogoniometry: An Electrocardiographic, Non-Invasive and Stress-Free Method for Detecting Cardiac Ischemia

Sanz, Ee. Schüpbach, M. Cardiogoniometry: an electrocardiographic, non-invasive and stress-free method for the detection of cardiac ischemia. GMS Medical Informatics, Biometry and Epidemiology. 5 (2009).


Applicability of Cardiogoniometry as a Non-Invasive Screening Tool for the Detection of Graft Vasculopathy in Heart Transplant Recipients

Spiliopoulos S, Hergesell V, Fischer D, Dapunt O, Krueger U, Koerfer R, Tenderich G. Applicability of cardiogoniometry as a non-invasive screening tool for the detection of graft vasculopathy in heart transplant recipients. Interact Cardiovasc Thorac Surg. 2016 Dec;23(6):976-978.


Computer Analysis of the Corrected, Orthogonal Cardiogram

von Mengden, H.J., Brodda, K. Computer analysis of the corrected, orthogonal cardiogram. Archiv für Kreislaufforschung 67, 123–141 (1972).


Assessment of the Spatial QRS-T Angle by Vectorcardiography: Current Data and Perspectives

Voulgari C, Tentolouris N. Assessment of the Spatial QRS-T Angle by Vectorcardiography: Current Data and Perspectives. Curr Cardiol Rev. 2009 Nov;5(4):251-62. doi: 10.2174/157340309789317850. Erratum in: Curr Cardiol Rev. 2010 Nov;6(4):373.


Improved Evaluation of Left Ventricular Hypertrophy Using the Spatial QRS-T Angle by Electrocardiography

Maanja, M., Schlegel, T.T., Kozor, R. et al. Improved evaluation of left ventricular hypertrophy using the spatial QRS-T angle by electrocardiography. Sci Rep 12, 15106 (2022).