Frankfurt, March 10, 2020: Following the initial clinical study published in the Journal of Electrocardiography in December, a second, independent study now confirms the effectiveness of cardisiography in the detection of coronary artery disease (CAD). In the study, the cardisography results compare well to those from the current gold standard, coronary angiography.

The team led by Dr. Temirlan Erkenov from the cardiac surgery department of the SANA heart center in Cottbus, Germany, concluded that: “cardisiography is a simple, precise and highly valid method that can be used as a non-invasive diagnostic modality for the initial assessment of stable CAD in a clinical setting.” (Cardisiography as a novel non-invasive diagnostic tool for the detection of coronary artery disease at rest – a first prospective study of diagnostic accuracy; Temirlan Erkenvo, Tomasz Stankowski, Oliver Grimmig, Sören Just, Prof. Oleg Remizov, Prof. Dirk Fritsche)

The study is based on data from 106 patients who underwent a coronary angiography as well as a cardisiography. The tests were correlated with that of the coronary angiography. The result: coronary angiography confirmed vascular disease in a total of 86 of the 106 patients. Cardisiography identified 82 of the 86 cases (95.4 percent), while only 12 cases were recognized in conventional echocardiography. This results in a sensitivity of 95.4 percent for cardisiography, a specificity of 90 percent and a positive predictive value of 97.6 percent for the CAD.

According to the authors: “In western countries, coronary artery disease is one of the most common causes of death and a common cause of physical disabilities. The reason for the severe course that the initial manifestation of the disease typically is a heart attack or sudden cardiac death. Cardisiography is a new, easy-to-use and examiner-independent technology that uses vectorcardiography combined with artificial Intelligence.”

You can find the abstract here.