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Clinical Research

The great potential of cardisiography lies in the early detection of coronary artery disease (CAD) in people who are still completely symptom-free and whose health status does not allow the blood circulation status to be determined. The studies show results that demonstrate the clear benefit of the method for early detection of poor blood flow to the heart muscle.

Cardisio peer-review study

Frankfurt, January 16, 2020: In the current issue, the renowned journal “Journal of Electrocardiology” publishes a peer-review study, which demonstrates the impressive precision of cardisiography in the screening of coronary heart diseases. The article provides results on the sensitivity and specificity of cardisiography: The sensitivity is 97% in the male subjects and 90% in the female subjects, i.e. 97% oin the study were 76% ahead of the men with 74%, i.e. 76% of healthy women are recognized as healthy and 74% of men. The Cardisiography is the first procedure that can be used to determine the risk of coronary artery disease (CHD) in symptom-free people non-invasively, quickly and cheaply.


Cardisio validation study Sana-Herzzentrum Cottbus

Frankfurt, March 10, 2020: For the second time in a short time, a clinical study comes to the conclusion that cardisiography in the detection of coronary artery disease (CAD) achieves comparably good results than the current gold standard, coronary angiography.

The team around Dr. Temirlan Erkenov from the cardiac surgery department of the SANA cardiac center in Cottbus, Germany, came to the conclusion that “… cardisiography is a simple, precise and highly valid method that can be used as a non-invasive diagnostic modality for the initial assessment of stable CAD in clinical Setting is suitable… ”(Cardisiography as a novel non-invasive diagnostic tool for the detection of coronary artery disease at rest – a first prospective study of diagnostic accuracy; Temirlan Erkenvo, Tomasz Stankowski, Oliver Grimmig, Sören Just, Prof. Oleg Remizov, Prof Dirk Fritsche)

The study included data from 106 patients in whom coronary angiography was indicated and was carried out. Cardiography was then performed, the result of which was correlated blindly with that of coronary angiography. The result: Coronary angiography confirmed vascular disease in a total of 86 of the 106 patients. Cardisiography identified 82 of the 86 cases (95.4 percent), while only 12 cases were recognized in conventional echocardiography. This results in a sensitivity of 95.4 percent for cardisiography, a specificity of 90 percent and a positive predictive value of 97.6 percent for the CAD.

“In western countries, coronary artery disease is one of the most common causes of death and a common cause of physical disabilities. The reason for the severe course is the fact that the initial manifestation of the disease can be a heart attack or sudden cardiac death. Cardisiography is a new, easy-to-use and examiner-independent technology that uses vector cardiography with the modern analysis options of artificial intelligence, ”the authors explain the reason for carrying out the study – and for its convincing course.

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A study at the Heart and Diabetes Center of North Rhine-Westphalia in Bad Oeynhausen confirms the diagnostic relevance of cardisiography

Comparison of cardisiography (CSG) with myocardial SPECT in suspected and known CAD:

  • Cardisiography (CSG) shows a significant connection with MPS in the preliminary diagnosis of CAD
  • A normal CSG correlates with a normal to slightly pathological MPS, correspondingly high negative predictive value of 98%
  • The CSG is suitable as a preselection tool for general practitioners or cardiology practices when deciding on non-invasive imaging in patients with suspected CHD