The Cardisio heart screening test, called Cardisiography, is the only screening method that is completely non-invasive, does not require medical staff to administer, and at the same time yields highly accurate results. The screening is easy to perform and can be provided at low cost.
The problem & the solution
According to the Centers for Disease Control, coronary artery disease (CAD) is the most common type of heart disease in the United States. It is estimated that one in three men and one in five women are affected by coronary artery disease, but don’t experience any symptoms. Until now there has not been an effective and non-invasive test to widely screen for CAD, and therefore many people only learn about their disease when they experience a heart attack.
Cardisio aims to address this problem by introducing Cardisiography, a new test that not only delivers accurate results very within a few minutes, but also compares each test with thousands of datasets stored in the Cardisio HealthNet. Therefore, Cardisiography delivers intelligently evaluated results, which have been compared to relevant risk groups and factors.
The Cardisio heart screening test (Cardisiography) is a highly accurate test to determine a risk factor for coronary heart disease with a sensitivity of 98% and a specificity of 85%. It is a non-invasive, examiner-independent, reproducible, fast and cost-effective screening procedure for the detection of haemodynamic relevant stenoses of the coronary arteries at rest. With its high reliability and easy application, the Cardisio screening test offers a complementary approach to legacy screening methods including electrocardiogram (ECG), stress ECG and echocardiography.
Other procedures like Myocardial Perfusion Scintigraphy (MPS), Coronary Computer Tomography (CCT) or Cardiac Magnetic Resonance Imaging (MRI) require considerable equipment, personnel, and the presence of a supervising physician that all represent a significant cost factor.
|ECG Exercise Test||1||3||60%||75%||≈ $200|
|Stress Echocardiography||1-3||3-4||88%||75%||≈ $400|
|Cardio CT||1||3||89%||87%||≈ $800|
|Coronary Angiogram||5||5||100%||100%||≈ $6,500|
Cardisio Graph & Cardisio App
The Cardisio Graph is the measuring device. It connects to a laptop running the Cardisio app in a web browser. Five electrodes, connected to the Cardisio Graph, are applied to the upper body of the test person. The test is initiated on the Cardiso app, is uploaded into the Cardisio Cloud (see below), which within minutes delivers the test results back to the app.
The Cardisio Cloud is a proprietary algorithm that performs data analysis and determines the risk factor. It is a deep learning system that, in combination with artificial intelligence, constantly evolves to make intelligent inferences via big data analysis.
Cardisiography's scientific approach
Cardisiography is based on a 3-dimensional scan of the heart. It relies on automated analysis, eliminating room for human error in diagnosing. The screening is done via a computer-based infinitesimal, three-dimensional calculation of the excitation processes of the mammalian heart based on a specific algorithm, in conjunction with a neural network correlated to the intrinsic blood as well as the specific spatial orientation of the myocardium in the dipole field as a function of time starting from a defined point.
Cardisiography delivers graphic representations of the electro-physical characteristics of the heart. It utilizes machine-based learning to continuously optimize its own algorithm. In development, the Cardisio screening test was correlated with matching representative cohorts, including over 500 patients with clinical indication for a coronary angiogram.